Indomethacin in the Treatment of Rheumatic Diseases.

نویسندگان

  • J S PERCY
  • P STEPHENSON
  • M THOMPSON
چکیده

Indomethacin is an indole-3-acetic acid derivative (Fig. 1), which has been shown by animal experiments to possess powerful anti-inflammatory and anti-pyretic properties without evidence of toxicity other than causing diarrhoea and gastro-intestinal irritation when given in excessive dosage (Hodgkinson, 1963). Preliminary reports of its action in arthritic patients have been given at the American Rheumatism Association meeting (1963), at the European Congress of Rheumatology (1963), and by Hart and Boardman (1963). The dangers of gastro-duodenal ulceration during therapy have been stressed by Norcross (1963) and by Lovgren and Allander (1964).

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عنوان ژورنال:
  • Annals of the rheumatic diseases

دوره 23  شماره 

صفحات  -

تاریخ انتشار 1964